Description
Oxifem SMF capsules is a dietary supplement designed to support oral health, specifically in the treatment of submucous fibrosis (SMF). Oral submucous fibrosis (OSMF) is a chronic, progressive condition characterized by the formation of fibrous bands in the oral cavity, particularly in the submucosal layer of the oral mucosa. This condition primarily affects the oral mucosa, the membrane lining the inside of the mouth.
Curcumin is known to inhibit the cytokine storm induced by areca nut and prevent fibrosis of the oral cavity. Various studies have shown that curcumin could inhibit the symptoms related to this disease, such as burning sensation, and improve mouth opening, and tongue protrusion through the modulation of various biochemical processes and molecules. Curcumin was found to modulate multiple hallmarks of several fibrosis disorders characterized by cytokine storm, oxidative stress, collagen synthesis, and expression of matrix metalloproteinases. As curcumin is a safe and affordable agent, it has remarkable potential in the prevention and treatment of OSF.
Each soft gelatin capsule contains :
- Lycopene 5 mg
- Beta-Carotene 10 mg
- Alpha Lipoic acid 50 mg
- Elemental copper 1 mg
- Elemental Selenium 75 mcg
- Vitamin E – 10 I.U
- Zinc sulphate – 27.45 mg
- Curcuma longa dry extract – 300 mg(95% Curcumin)
- Piper nigrum extract 5 mg ( 95% Piperine)
Antioxidants and Anti-Inflammatory Compounds in Oxifem SMF:
1. Lycopene (5mg): A potent antioxidant that helps protect cells from damage and reduce inflammation.
2. Beta-carotene (10mg): A precursor to vitamin A that acts as an antioxidant and helps maintain healthy mucous membranes.
3. Alpha-lipoic acid (50mg): An antioxidant that helps reduce oxidative stress and inflammation.
4. Curcuma longa dry extract (95% curcumin) (300mg): Curcumin is a powerful anti-inflammatory compound that helps reduce inflammation and oxidative stress.
Essential Minerals
1. Elemental copper (1mg): Copper is essential for maintaining healthy connective tissue and supporting immune function.
2. Elemental selenium (75mcg): Selenium acts as an antioxidant and helps protect cells from damage.
3. Zinc sulphate (27.45mg): Zinc is essential for maintaining healthy immune function, wound healing, and protein synthesis.
Bioavailability Enhancer
1. Piper nigrum extract (95% piperine) (5mg): Piperine is a bioavailability enhancer that helps increase the absorption of other nutrients.
Potential Benefits of Oxifem SMF in the treatment of Oral Submucous fibrosis are enumerated below :
1. Reduced inflammation and oxidative stress: The antioxidants and anti-inflammatory compounds in Oxifem SMF capsules helps reduce inflammation and oxidative stress in the oral mucosa.
2. Improved oral health: The essential minerals and antioxidants in Oxifem SMF capsules helps maintain healthy oral mucosa and reduce the risk of oral complications.
3. Enhanced wound healing: The zinc and other nutrients in Oxifem SMF capsules helps support wound healing and tissue repair in the oral cavity.






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